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MV Journal club: Intermittent NIV after extubation in patients with chronic respiratory disorders

By: Marcelo Alcantara, Médico - 12/25/2017 19:48

Dear XLUNG subscribers,

An interesting paper was published in Intensive Care Medicine by Fréderic Vargas et al., from Bordeaux, France.

Vargas, F., Clavel, M., Sanchez-Verlan, P. et al. Intensive Care Med (2017) 43: 1626. https://doi.org/10.1007/s00134-017-4785-1

The authors studied the effect of intermittent NIV in patients with chronic respiratory disorders in preventing respiratory failure and other relevant outcomes, such as reintubation rate, length of ICU stay and mortality

One-hundred and forty-four patients with chronic respiratory disorders, but not necessarily hypercapnic, were randomly allocated after extubation to receive either NIV (NIV group, n = 72), performed with a discontinuous approach, for the first 48 h, or conventional oxygen treatment (usual care group, n = 72). The primary endpoint was decreased respiratory failure within 48 h after extubation.

The study showed positive results concerning the effect of NIV in comparison to conventional oxygen therapy.

Would you like to discuss the paper and the XLUNG point of view about the manuscript?

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Take me to this paper in the ICM journal 

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